Anti-FLNA Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-FLNA Polyclonal Antibody

品牌:solarbio | 货号:K005538P

英文名称 Anti-FLNA Polyclonal Antibody
宿主 Rabbit
别名 ABP-280;ABPX;CSBS;CVD1;FLN;FLN-A;FLN1;FMD;MNS;NHBP;OPD;OPD1;OPD2;XLVD;XMVD
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 281kDa
Gene ID 2316
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human FLNA
性状 液体
Public Immunogen Range A synthetic peptide of human FLNA
Subcellular Locations Cytoplasm cell cortex cytoskeleton
Swiss Prot P21333
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.