Anti-SSRP1 Polyclonal Antibody
品牌：solarbio | 货号：K004506P
| 英文名称 | Anti-SSRP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FACT;FACT80;T160 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 81kDa |
| Gene ID | 6749 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SSRP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SSRP1 |
| Subcellular Locations | Chromosome Nucleus nucleolus |
| Swiss Prot | Q08945 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. |