Anti-CAV3 Polyclonal Antibody
品牌:solarbio | 货号:K005652P
英文名称 |
Anti-CAV3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LGMD1C;LQT9;VIP-21;VIP21 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
17kDa |
Gene ID |
859 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CAV3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CAV3 |
Subcellular Locations |
Cell membrane Golgi apparatus membrane Membrane Peripheral membrane protein caveola |
Swiss Prot |
P56539 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. |