Anti-CAV3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CAV3 Polyclonal Antibody

品牌:solarbio | 货号:K005652P

英文名称 Anti-CAV3 Polyclonal Antibody
宿主 Rabbit
别名 LGMD1C;LQT9;VIP-21;VIP21
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 17kDa
Gene ID 859
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CAV3
性状 液体
Public Immunogen Range Recombinant protein of human CAV3
Subcellular Locations Cell membrane Golgi apparatus membrane Membrane Peripheral membrane protein caveola
Swiss Prot P56539
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.