Anti-TMEM43 Polyclonal Antibody
品牌：solarbio | 货号：K005884P
| 英文名称 | Anti-TMEM43 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARVC5;ARVD5;EDMD7;LUMA |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 45kDa |
| Gene ID | 79188 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TMEM43 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TMEM43 |
| Subcellular Locations | Endoplasmic reticulum Multi-pass membrane protein Nucleus inner membrane |
| Swiss Prot | Q9BTV4 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. |