Anti-NEFL Polyclonal Antibody
品牌：solarbio | 货号：K006633P
| 英文名称 | Anti-NEFL Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NFL;NF-L;NF68;CMT1F;CMT2E |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 62kDa |
| Gene ID | 4747 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NEFL |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NEFL |
| Subcellular Locations | Cell membrane |
| Swiss Prot | P07196 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |