Anti-NF2 Polyclonal Antibody
品牌：solarbio | 货号：K003352P
| 英文名称 | Anti-NF2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACN;BANF;SCH |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000 IF 1:20-100. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 70kDa |
| Gene ID | 4771 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NF2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NF2 |
| Subcellular Locations | Cell projection Cytoplasm Cytoplasmic granule Cytoplasmic side Nucleus Nucleus Peripheral membrane protein cytoskeleton filopodium membrane perinuclear region ruffle membrane |
| Swiss Prot | P35240 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. |