Anti-FLNB Polyclonal Antibody
品牌:solarbio | 货号:K003356P
英文名称 |
Anti-FLNB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ABP-278;ABP-280;AOI;FH1;FLN-B;FLN1L;LRS1;SCT;TABP;TAP |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-1000. IHC 1:50-100. IF 1:20-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
278kDa |
Gene ID |
2317 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human FLNB |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human FLNB |
Subcellular Locations |
Cytoplasm Z line cell cortex cytoskeleton myofibril sarcomere |
Swiss Prot |
O75369 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |