Anti-CCL3L1 Polyclonal Antibody
品牌:solarbio | 货号:K003507P
英文名称 |
Anti-CCL3L1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
464.2;D17S1718;G0S19-2;LD78;LD78-beta(1-70);LD78BETA;MIP1AP;SCYA3L;SCYA3L1 |
应用 |
WB |
稀释比例 |
WB 1:200-500. |
交叉反应 |
Human |
蛋白分子量 |
10kDa |
Gene ID |
6349 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CCL3L1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CCL3L1 |
Subcellular Locations |
Secreted |
Swiss Prot |
P16619 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants. |