Anti-PIDD Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PIDD Polyclonal Antibody

品牌:solarbio | 货号:K003850P

英文名称 Anti-PIDD Polyclonal Antibody
宿主 Rabbit
别名 PIDD1;PIDD;LRDD;
应用 WB IF
稀释比例 WB 1:500-1000. IF 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 100kDa
Gene ID 55367
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant Protein of human PIDD
性状 液体
Public Immunogen Range Recombinant Protein of human PIDD
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q9HB75
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.