Anti-PIDD Polyclonal Antibody
品牌:solarbio | 货号:K003850P
英文名称 |
Anti-PIDD Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PIDD1;PIDD;LRDD; |
应用 |
WB IF |
稀释比例 |
WB 1:500-1000. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
100kDa |
Gene ID |
55367 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant Protein of human PIDD |
性状 |
液体 |
Public Immunogen Range |
Recombinant Protein of human PIDD |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q9HB75 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. |