Anti-GCLM Polyclonal Antibody
品牌:solarbio | 货号:K003905P
| 英文名称 | Anti-GCLM Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GLCLR |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 31kDa |
| Gene ID | 2730 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GCLM |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GCLM |
| Subcellular Locations | Cytosol |
| Swiss Prot | P48507 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |