Anti-FMOD Polyclonal Antibody
品牌:solarbio | 货号:K004472P
英文名称 |
Anti-FMOD Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
FM;SLRR2E |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
43kDa |
Gene ID |
2331 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human FMOD |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human FMOD |
Subcellular Locations |
Secreted extracellular matrix extracellular space |
Swiss Prot |
Q06828 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. |