Anti-TBC1D4 Polyclonal Antibody
品牌：solarbio | 货号：K007864P
| 英文名称 | Anti-TBC1D4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AS160 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 147kDa |
| Gene ID | 9882 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TBC1D4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TBC1D4 |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | O60343 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | TBC1 domain family member 4 (TBC1D4), also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD), sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time. |