Anti-TRIM71 Polyclonal Antibody
品牌:solarbio | 货号:K007870P
英文名称 |
Anti-TRIM71 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LIN41;LIN-41 |
应用 |
WB |
稀释比例 |
WB 1:1000-5000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
93kDa |
Gene ID |
131405 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human TRIM71 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human TRIM71 |
Swiss Prot |
Q2Q1W2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
LIN-41, also called tripartite motif-containing 71 (TRIM71), which was first identified in Caenorhabditis elegans, is responsible for the timing of cell fate determination. By encoding microRNAs (miRNAs), the heterochronic genes let-7 and lin-4 downregulate the gene encoding LIN-41. The miRNAs bind to six complementary sites on the 3′ untranslated region (UTR) of the LIN-41 gene. This downregulation positively regulates the timing of the expression of LIN-29, an adult specification transcription factor.? |