Anti-ADAM15 Polyclonal Antibody
品牌:solarbio | 货号:K008285P
英文名称 |
Anti-ADAM15 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MDC15 |
应用 |
IHC |
稀释比例 |
IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
93/86kDa |
Gene ID |
8751 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ADAM15 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ADAM15 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q13444 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |