Anti-ADAM15 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ADAM15 Polyclonal Antibody

品牌:solarbio | 货号:K008285P

英文名称 Anti-ADAM15 Polyclonal Antibody
宿主 Rabbit
别名 MDC15
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 93/86kDa
Gene ID 8751
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ADAM15
性状 液体
Public Immunogen Range Recombinant protein of human ADAM15
Subcellular Locations Cytoplasm
Swiss Prot Q13444
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.