Anti-ADAM15 Polyclonal Antibody
品牌：solarbio | 货号：K008285P
| 英文名称 | Anti-ADAM15 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MDC15 |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 93/86kDa |
| Gene ID | 8751 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ADAM15 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ADAM15 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q13444 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |