Anti-ALS2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ALS2 Polyclonal Antibody

品牌:solarbio | 货号:K008298P

英文名称 Anti-ALS2 Polyclonal Antibody
宿主 Rabbit
别名 ALSJ;PLSJ;IAHSP;ALS2CR6
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 184/43/87kDa
Gene ID 57679
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ALS2
性状 液体
Public Immunogen Range Recombinant protein of human ALS2
Subcellular Locations Cytoplasm
Swiss Prot Q96Q42
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.