Anti-ATG4D Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ATG4D Polyclonal Antibody

品牌:solarbio | 货号:K008329P

英文名称 Anti-ATG4D Polyclonal Antibody
宿主 Rabbit
别名 APG4D;AUTL4;APG4-D
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 53/16kDa
Gene ID 84971
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ATG4D
性状 液体
Public Immunogen Range Recombinant protein of human ATG4D
Subcellular Locations Cytoplasm
Swiss Prot Q86TL0
克隆类型 Polyclonal Antibody
背景资料 Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes.