Anti-ATG4D Polyclonal Antibody
品牌:solarbio | 货号:K008329P
英文名称 |
Anti-ATG4D Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
APG4D;AUTL4;APG4-D |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
53/16kDa |
Gene ID |
84971 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ATG4D |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ATG4D |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q86TL0 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |