Anti-RICTOR Polyclonal Antibody
品牌:solarbio | 货号:K008337P
英文名称 |
Anti-RICTOR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PIA;AVO3;hAVO3 |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
192/29/195kDa |
Gene ID |
253260 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human RICTOR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human RICTOR |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q6R327 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Rapamycin-insensitive companion of mTOR?is a?protein?that in humans is encoded by the?RICTOR?gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. |