Anti-RICTOR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-RICTOR Polyclonal Antibody

品牌:solarbio | 货号:K008337P

英文名称 Anti-RICTOR Polyclonal Antibody
宿主 Rabbit
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 192/29/195kDa
Gene ID 253260
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human RICTOR
性状 液体
Public Immunogen Range Recombinant protein of human RICTOR
Subcellular Locations Cytoplasm
Swiss Prot Q6R327
克隆类型 Polyclonal Antibody
背景资料 Rapamycin-insensitive companion of mTOR?is a?protein?that in humans is encoded by the?RICTOR?gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.