Anti-RNF7 Polyclonal Antibody
品牌：solarbio | 货号：K005154P
| 英文名称 | Anti-RNF7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CKBBP1;ROC2;SAG |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:20-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 13kDa |
| Gene ID | 9616 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RNF7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RNF7 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9UBF6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. |