Anti-RNF7 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-RNF7 Polyclonal Antibody

品牌:solarbio | 货号:K005154P

英文名称 Anti-RNF7 Polyclonal Antibody
宿主 Rabbit
别名 CKBBP1;ROC2;SAG
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:20-50.
交叉反应 Human Mouse Rat
蛋白分子量 13kDa
Gene ID 9616
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human RNF7
性状 液体
Public Immunogen Range Recombinant protein of human RNF7
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q9UBF6
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.