Anti-SF3B2 Polyclonal Antibody
品牌：solarbio | 货号：K004274P
| 英文名称 | Anti-SF3B2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Cus1;SAP145;SF3B145;SF3b1;SF3b150 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 100kDa |
| Gene ID | 10992 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SF3B2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SF3B2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q13435 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron’s branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. |