Anti-IDH2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IDH2 Polyclonal Antibody

品牌:solarbio | 货号:K005073P

英文名称 Anti-IDH2 Polyclonal Antibody
宿主 Rabbit
别名 D2HGA2;ICD-M;IDH;IDHM;IDP;IDPM;mNADP-IDH
应用 WB IHC IF IP ChIP
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:20-50. IP 1:50-200. ChIP 1:20-100.
交叉反应 Human Mouse Rat
蛋白分子量 51kDa
Gene ID 3418
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human IDH2
性状 液体
Public Immunogen Range Recombinant protein of human IDH2
Subcellular Locations Mitochondrion
Swiss Prot P48735
克隆类型 Polyclonal Antibody
背景资料 Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.