Anti-ECH1 Polyclonal Antibody
品牌:solarbio | 货号:K007468P
| 英文名称 | Anti-ECH1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HPXEL |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-300. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 36kDa |
| Gene ID | 1891 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ECH1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ECH1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q13011 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |