Anti-EDNRB Polyclonal Antibody
品牌:solarbio | 货号:K003529P
英文名称 |
Anti-EDNRB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ABCDS;ET-B;ET-BR;ETB;ETB1;ETBR;ETRB;HSCR;HSCR2;WS4A |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
50kDa |
Gene ID |
1910 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human EDNRB |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human EDNRB |
Subcellular Locations |
Cell membrane Multi-pass membrane protein |
Swiss Prot |
P24530 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. |