Anti-F3 Polyclonal Antibody
品牌：solarbio | 货号：K006840P
| 英文名称 | Anti-F3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TF;TFA;CD142 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 33kDa |
| Gene ID | 2152 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human F3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human F3 |
| Subcellular Locations | Membrane |
| Swiss Prot | P13726 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants. |