Anti-GNA11 Polyclonal Antibody
品牌：solarbio | 货号：K003471P
| 英文名称 | Anti-GNA11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FBH;FBH2;FHH2;GNA-11;HHC2;HYPOC2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 42kDa |
| Gene ID | 2767 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GNA11 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GNA11 |
| Subcellular Locations | Cell membrane Cytoplasm Lipid-anchor |
| Swiss Prot | P29992 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. |