Anti-BBS2 Polyclonal Antibody
品牌:solarbio | 货号:K005238P
英文名称 |
Anti-BBS2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BBS;RP74 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Mouse Rat |
蛋白分子量 |
80kDa |
Gene ID |
583 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human BBS2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human BBS2 |
Subcellular Locations |
Cell projection Cytoplasm centriolar satellite centrosome cilium membrane cytoskeleton microtubule organizing center |
Swiss Prot |
Q9BXC9 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins. |