Anti-TNFSF18 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TNFSF18 Polyclonal Antibody

品牌:solarbio | 货号:K106930P

英文名称 Anti-TNFSF18 Polyclonal Antibody
宿主 Rabbit
别名 AITRL;GITRL;TL6;hGITRL
应用 WB
稀释比例 WB 1:8000-12000.
交叉反应 Mouse
蛋白分子量 46kDa
Gene ID 8995
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TNFSF18
性状 液体
Public Immunogen Range A synthetic peptide of human TNFSF18
Subcellular Locations Cell membrane?
Swiss Prot Q9UNG2
克隆类型 Polyclonal Antibody
背景资料 Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).