Anti-INSR Polyclonal Antibody
品牌：solarbio | 货号：K106883P
| 英文名称 | Anti-INSR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD220;HHF5;insulin receptor |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 156kDa |
| Gene ID | 3643 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human INSR |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human INSR |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P06213 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. |