Anti-CXCR3 Polyclonal Antibody
品牌:solarbio | 货号:K106523P
英文名称 |
Anti-CXCR3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD182;CD183;CKR-L2;CMKAR3;GPR9;IP10-R;Mig-R;MigR |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
48kDa |
Gene ID |
12766 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CXCR3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CXCR3 |
Subcellular Locations |
Cytoplasm Cell membrane |
Swiss Prot |
P49682 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). |