Anti-CTNNAL1 Polyclonal Antibody
品牌:solarbio | 货号:K008119P
英文名称 |
Anti-CTNNAL1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACRP;CLLP;alpha-CATU |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
82kDa |
Gene ID |
8727 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CTNNAL1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CTNNAL1 |
Swiss Prot |
Q9UBT7 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
CTNNAL1 (catenin (cadherin-associated protein), alpha-like 1), also known as CLLP or alpha-CATU, is a 734 amino acid cytoplasmic peripheral membrane protein belonging to the vinculin/alpha-catenin family. Expressed at high levels in adrenal gland and present at lower levels in neural tissues, CTNNAL1 may be involved in the regulation of Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor 1 (RhoGEF p115). It is suggested that CTNNAL1 is down-regulated in pancreatic carcinoma undergoing differentiation and apoptosis. Existing as three isforms produced by alternative splicing events, CTNNAL1 may contribute to the wound repair and proliferation of human bronchial epithelial cells (HBEC). |