Anti-CTNNAL1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CTNNAL1 Polyclonal Antibody

品牌:solarbio | 货号:K008119P

英文名称 Anti-CTNNAL1 Polyclonal Antibody
宿主 Rabbit
别名 ACRP;CLLP;alpha-CATU
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse
蛋白分子量 82kDa
Gene ID 8727
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CTNNAL1
性状 液体
Public Immunogen Range Recombinant protein of human CTNNAL1
Swiss Prot Q9UBT7
克隆类型 Polyclonal Antibody
背景资料 CTNNAL1 (catenin (cadherin-associated protein), alpha-like 1), also known as CLLP or alpha-CATU, is a 734 amino acid cytoplasmic peripheral membrane protein belonging to the vinculin/alpha-catenin family. Expressed at high levels in adrenal gland and present at lower levels in neural tissues, CTNNAL1 may be involved in the regulation of Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor 1 (RhoGEF p115). It is suggested that CTNNAL1 is down-regulated in pancreatic carcinoma undergoing differentiation and apoptosis. Existing as three isforms produced by alternative splicing events, CTNNAL1 may contribute to the wound repair and proliferation of human bronchial epithelial cells (HBEC).