Anti-KIRREL2 Polyclonal Antibody
品牌:solarbio | 货号:K007123P
英文名称 |
Anti-KIRREL2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NLG1;NEPH3;FILTRIN |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
75kDa |
Gene ID |
84063 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human KIRREL2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human KIRREL2 |
Subcellular Locations |
Plasma membrane |
Swiss Prot |
Q6UWL6 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
NEPH3 (nephrin-like protein 3), also referred to as NLG1, FILTRIN or KIRREL2 (kin of IRRE like 2), is a 708 amino acid protein that is a member of the immunoglobulin superfamily of cell adhesion molecules. NEPH3 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues. NEPH3 localizes to the interpodocyte filtration slit in the kidney and to the Langerhans islet beta cells in the pancreas. NEPH3 is thought to be involved in the maintenance of the glomerular filtration barrier in the kidney and in pancreas development.? |