Anti-HYAL3 Polyclonal Antibody
品牌:solarbio | 货号:K007070P
英文名称 |
Anti-HYAL3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LUCA3;HYAL-3;LUCA-3 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Rat |
蛋白分子量 |
47kDa |
Gene ID |
8372 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human HYAL3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human HYAL3 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
O43820 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. |