Anti-CAST Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CAST Polyclonal Antibody

品牌:solarbio | 货号:K006968P

英文名称 Anti-CAST Polyclonal Antibody
宿主 Rabbit
别名 BS-17
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:100-300.
交叉反应 Human
蛋白分子量 77kDa
Gene ID 831
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CAST
性状 液体
Public Immunogen Range Recombinant protein of human CAST
Subcellular Locations Cytoplasm
Swiss Prot P20810
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.