Anti-CAST Polyclonal Antibody
品牌：solarbio | 货号：K006968P
| 英文名称 | Anti-CAST Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BS-17 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| 交叉反应 | Human |
| 蛋白分子量 | 77kDa |
| Gene ID | 831 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CAST |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CAST |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P20810 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |