Anti-Phospho-PKCδ/θ-S643/676 Polyclonal Antibody
品牌：solarbio | 货号：K006239P
| 英文名称 | Anti-Phospho-PKCδ/θ-S643/676 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PRKCT;nPKC-theta; |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 78kDa |
| Gene ID | 5580/5588 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S643/676 of human PKCδ/θ |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S643/676 of human PKCδ/θ |
| Subcellular Locations | Nucleus Plasma membrane |
| Swiss Prot | Q05655; Q04759 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. |