Anti-ALDH7A1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ALDH7A1 Polyclonal Antibody

品牌:solarbio | 货号:K005948P

英文名称 Anti-ALDH7A1 Polyclonal Antibody
宿主 Rabbit
别名 ATQ1;EPD;PDE
应用 WB IHC IF
稀释比例 WB 1:1000-4000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 58kDa
Gene ID 501
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ALDH7A1
性状 液体
Public Immunogen Range Recombinant protein of human ALDH7A1
Subcellular Locations Cytoplasm Mitochondrion Nucleus cytosol
Swiss Prot P49419
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.