Anti-ALDH7A1 Polyclonal Antibody
品牌：solarbio | 货号：K005948P
| 英文名称 | Anti-ALDH7A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ATQ1;EPD;PDE |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:1000-4000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 58kDa |
| Gene ID | 501 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ALDH7A1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ALDH7A1 |
| Subcellular Locations | Cytoplasm Mitochondrion Nucleus cytosol |
| Swiss Prot | P49419 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. |