Anti-PLCG1 Polyclonal Antibody
品牌：solarbio | 货号：K005405P
| 英文名称 | Anti-PLCG1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NCKAP3;PLC-II;PLC1;PLC148;PLCgamma1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 149kDa |
| Gene ID | 5335 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human PLCG1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human PLCG1 |
| Subcellular Locations | Cell projection lamellipodium ruffle |
| Swiss Prot | P19174 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |