Anti-CDH23 Polyclonal Antibody
品牌:solarbio | 货号:K003485P
| 英文名称 | Anti-CDH23 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDHR23;USH1D |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 369kDa |
| Gene ID | 64072 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CDH23 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CDH23 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | Q9H251 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. |