Anti-CDH23 Polyclonal Antibody
品牌:solarbio | 货号:K003485P
英文名称 |
Anti-CDH23 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CDHR23;USH1D |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:100-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
369kDa |
Gene ID |
64072 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CDH23 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CDH23 |
Subcellular Locations |
Cell membrane Single-pass type I membrane protein |
Swiss Prot |
Q9H251 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. |