Anti-GEN1 Polyclonal Antibody
品牌：solarbio | 货号：K001802P
| 英文名称 | Anti-GEN1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Gen |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 蛋白分子量 | 103kDa |
| Gene ID | 348654 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GEN1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GEN1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q17RS7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. |