Anti-DYNC2LI1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-DYNC2LI1 Polyclonal Antibody

品牌:solarbio | 货号:K003844P

英文名称 Anti-DYNC2LI1 Polyclonal Antibody
宿主 Rabbit
别名 CGI-60;D2LIC;LIC3
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 40kDa
Gene ID 51626
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human DYNC2LI1
性状 液体
Public Immunogen Range Recombinant protein of human DYNC2LI1
Subcellular Locations Cytoplasm cilium axoneme cytoskeleton
Swiss Prot Q8TCX1
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.