Anti-DYNC2LI1 Polyclonal Antibody
品牌:solarbio | 货号:K003844P
英文名称 |
Anti-DYNC2LI1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CGI-60;D2LIC;LIC3 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
40kDa |
Gene ID |
51626 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DYNC2LI1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DYNC2LI1 |
Subcellular Locations |
Cytoplasm cilium axoneme cytoskeleton |
Swiss Prot |
Q8TCX1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. |