Anti-HTR2B Polyclonal Antibody
品牌：solarbio | 货号：K004123P
| 英文名称 | Anti-HTR2B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 5-HT(2B);5-HT-2B;5-HT2B |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 54kDa |
| Gene ID | 3357 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HTR2B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HTR2B |
| Subcellular Locations | Cell junction Cell membrane Multi-pass membrane protein synapse synaptosome |
| Swiss Prot | P41595 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. |