Anti-ATP7B Polyclonal Antibody
品牌:solarbio | 货号:K004129P
英文名称 |
Anti-ATP7B Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PWD;WC1;WD;WND |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
157kDa |
Gene ID |
540 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ATP7B |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ATP7B |
Subcellular Locations |
Cytoplasm Golgi apparatus Golgi apparatus membrane Mitochondrion Multi-pass membrane protein Multi-pass membrane protein trans-Golgi network membrane |
Swiss Prot |
P35670 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). |