Anti-ATP7B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ATP7B Polyclonal Antibody

品牌:solarbio | 货号:K004129P

英文名称 Anti-ATP7B Polyclonal Antibody
宿主 Rabbit
别名 PWD;WC1;WD;WND
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-200.
交叉反应 Human Mouse
蛋白分子量 157kDa
Gene ID 540
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ATP7B
性状 液体
Public Immunogen Range Recombinant protein of human ATP7B
Subcellular Locations Cytoplasm Golgi apparatus Golgi apparatus membrane Mitochondrion Multi-pass membrane protein Multi-pass membrane protein trans-Golgi network membrane
Swiss Prot P35670
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).