Anti-SLC12A1 Polyclonal Antibody
品牌：solarbio | 货号：K008236P
| 英文名称 | Anti-SLC12A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BSC1;NKCC2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 121kDa |
| Gene ID | 6557 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SLC12A1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SLC12A1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q13621 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle’s loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven. |