Anti-SECISBP2 Polyclonal Antibody
品牌：solarbio | 货号：K004755P
| 英文名称 | Anti-SECISBP2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SBP2 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 95kDa |
| Gene ID | 79048 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SECISBP2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SECISBP2 |
| Subcellular Locations | Mitochondrion Nucleus |
| Swiss Prot | Q96T21 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants. |