Anti-PSMD8 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PSMD8 Polyclonal Antibody

品牌:solarbio | 货号:K004892P

英文名称 Anti-PSMD8 Polyclonal Antibody
宿主 Rabbit
别名 HEL-S-91n;HIP6;HYPF;Nin1p;Rpn12;S14;p31
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-100.
交叉反应 Human Mouse
蛋白分子量 40kDa
Gene ID 5714
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PSMD8
性状 液体
Public Immunogen Range Recombinant protein of human PSMD8
Subcellular Locations Cytosol Nucleus
Swiss Prot P48556
克隆类型 Polyclonal Antibody
背景资料 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.