Anti-CENPC Polyclonal Antibody
品牌:solarbio | 货号:K006987P
| 英文名称 | Anti-CENPC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MIF2;hcp-4;CENP-C;CENPC1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 107kDa |
| Gene ID | 1060 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CENPC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CENPC |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q03188 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. |