Anti-GRIA4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-GRIA4 Polyclonal Antibody

品牌:solarbio | 货号:K006773P

英文名称 Anti-GRIA4 Polyclonal Antibody
宿主 Rabbit
别名 GLUR4;GLURD;GluA4;GLUR4C
应用 IHC
稀释比例 IHC 1:50-300.
交叉反应 Human Mouse Rat
蛋白分子量 101kDa
Gene ID 2893
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human GRIA4
性状 液体
Public Immunogen Range A synthetic peptide of human GRIA4
Subcellular Locations Cell membrane
Swiss Prot P48058
克隆类型 Polyclonal Antibody
背景资料 Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.