Anti-GRIA4 Polyclonal Antibody
品牌:solarbio | 货号:K006773P
英文名称 |
Anti-GRIA4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
GLUR4;GLURD;GluA4;GLUR4C |
应用 |
IHC |
稀释比例 |
IHC 1:50-300. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
101kDa |
Gene ID |
2893 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human GRIA4 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human GRIA4 |
Subcellular Locations |
Cell membrane |
Swiss Prot |
P48058 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. |