Anti-GRIA4 Polyclonal Antibody
品牌:solarbio | 货号:K006773P
| 英文名称 | Anti-GRIA4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GLUR4;GLURD;GluA4;GLUR4C |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-300. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 101kDa |
| Gene ID | 2893 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human GRIA4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human GRIA4 |
| Subcellular Locations | Cell membrane |
| Swiss Prot | P48058 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. |