Anti-PDZK1 Polyclonal Antibody
品牌：solarbio | 货号：K003911P
| 英文名称 | Anti-PDZK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CAP70;CLAMP;NHERF-3;NHERF3;PDZD1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 57kDa |
| Gene ID | 5174 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PDZK1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PDZK1 |
| Subcellular Locations | Cell membrane Cytoplasm Membrane Peripheral membrane protein |
| Swiss Prot | Q5T2W1 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |