Anti-WHSC1 Polyclonal Antibody
品牌:solarbio | 货号:K007976P
英文名称 |
Anti-WHSC1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
WHS;NSD2;TRX5;MMSET;REIIBP |
应用 |
IHC |
稀释比例 |
IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
152/81/69/53/30kDa |
Gene ID |
7468 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human WHSC1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human WHSC1 |
Subcellular Locations |
Nucleus |
Swiss Prot |
O96028 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. |