Anti-MLPH Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MLPH Polyclonal Antibody

品牌:solarbio | 货号:K004688P

英文名称 Anti-MLPH Polyclonal Antibody
宿主 Rabbit
别名 SLAC2-A
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 66kDa
Gene ID 79083
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MLPH
性状 液体
Public Immunogen Range Recombinant protein of human MLPH
Subcellular Locations Cytoplasm
Swiss Prot Q9BV36
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.