Anti-RNF8 Polyclonal Antibody
品牌:solarbio | 货号:K005155P
英文名称 |
Anti-RNF8 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
hRNF8 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
56kDa |
Gene ID |
9025 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human RNF8 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human RNF8 |
Subcellular Locations |
Chromosome Midbody Nucleus telomere |
Swiss Prot |
O76064 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. |