Anti-PRAME Polyclonal Antibody
品牌:solarbio | 货号:K004543P
英文名称 |
Anti-PRAME Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CT130;MAPE;OIP-4;OIP4 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:20-50. |
交叉反应 |
Human |
蛋白分子量 |
58kDa |
Gene ID |
23532 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PRAME |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PRAME |
Subcellular Locations |
Cell membrane Nucleus |
Swiss Prot |
P78395 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. The encoded protein acts as a repressor of retinoic acid receptor and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. |